Feel clear about your Ocrevus injection

Emma, UK

Living with MS since 2018


On Ocrevus since 2018


Switched to Ocrevus SC in 2024

Emma, UK

Living with MS since 2018


On Ocrevus since 2018

Switched to Ocrevus SC in 2024

Feel clear about your Ocrevus injection

You and your medical team have decided that you will receive your treatment with Ocrevus as an injection under your skin (otherwise known as subcutaneous injection).1

 

Your first Ocrevus subcutaneous injection may be in hospital, though it could be carried out at home, depending on individual circumstances. You and your medical team can decide together.1

 

Ocrevus will be given to you by a doctor or nurse who’s experienced in using this treatment, and they’ll monitor you closely throughout your injection, in case you have any side effects.1  

pim

"Being on Ocrevus has been a massive game changer for me in terms of being able to remain stable with MS, leading a normal lifestyle."

Emma

Who has relapsing remitting MS (RRMS) on Ocrevus SC injection

What happens on the day?

Here’s what to expect from your first injection, so you can feel prepared.


Your Ocrevus injection will be given into the layer of fat under the skin, in your stomach area. You’ll have this procedure every 6 months. Your first injection may take place in hospital or it could be carried out at home, depending on your individual circumstances and if your service is able to support this.1

 

If you and your medical team decide, you may have your Ocrevus injections at home. Your dose of Ocrevus will be delivered to your home and will be administered by a trained healthcare professional. The healthcare professional will also administer your pre-medications and will have medications at hand, in case you experience any reactions.1

 

The injection itself takes about 10 minutes, but before it takes place you’ll be given pre-medication treatments to minimise potential injection reactions, and you’ll be monitored for an hour after your first dose to make sure you don’t have any problems.1 So, you can expect the treatment to take around 2 hours, though the overall time will vary from one person to another.


A nurse will run through a checklist to ensure you’re OK to have your injection – for example, they’ll check that you don’t have any infections such as flu. At this point, your healthcare professional may choose to run some additional tests before your injection.


Before your Ocrevus injection, you’ll be given other medications to help prevent or reduce possible reactions or side effects such as headache, nausea and itching.1

 

These pre-medications will be given to you orally and will include a steroid, an antihistamine, and may also include a drug that reduces fever (an antipyretic, like paracetamol).1


Your injection will be given by a doctor or nurse who’s experienced in providing Ocrevus treatment.1

 

To minimise discomfort, they will make sure the injection is given in an area of your stomach where the skin isn’t red, bruised, tender or hard. They will also avoid any places where you have moles or scars.1

 

Your doctor or nurse will watch you closely during the injection, in case you have any side effects.1 If you do have a reaction to the injection, you may be given medicines to treat it and the injection may need to be temporarily or permanently stopped, depending on the severity of the reaction.1


After your first injection, your doctor or nurse will continue to monitor you for at least 1 hour, to make sure you’re OK. For future doses, this observation is optional, so your doctor or nurse may decide it’s not necessary.

 

If your first dose was in hospital, your doctor or nurse may decide to give you your future doses at home, if appropriate for you.1

If you get a reaction during your injection or within 24 hours (such as a headache or nausea), tell your MS team straight away.1

Every 6 months, you’ll have another Ocrevus injection. Depending on what your medical team decide, you may have these in hospital or at home.1 This would involve a nurse coming to your home to give you the injections every 6 months.

 

If you miss an injection of Ocrevus, talk to your MS team to arrange to have it as soon as possible. Don’t wait until your next planned injection.1


PIM

"Take the opportunities to speak to people with MS… We're all going through it together."

Emma

Who has relapsing remitting MS (RRMS) on Ocrevus SC injection

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. Please report suspected side effects to the MHRA through the Yellow Card scheme, via the Yellow card website www.mhra.gov.uk/yellowcard, or the free Yellow Card app available in the Apple App Store or Google Play Store. You should also report side effects to Roche Products Ltd. by emailing the Roche Drug Safety Centre at welwyn.uk_dsc@roche.com or calling +44 (0) 1707 367554. By reporting side effects you can help provide more information on the safety of this medicine.

References:

  1. Ocrevus. Patient Information Leaflet. Ocrevus 920 mg Solution for Injection Ocrelizumab. Roche Products Limited.