Emma, UK
Living with MS since 2018
On Ocrevus since 2018
Switched to Ocrevus SC in 2024
Emma, UK
Living with MS since 2018
On Ocrevus since 2018
Switched to Ocrevus SC in 2024
Right now, you’ll probably have lots of questions about Ocrevus. Here’s a brief overview to help you understand what this medicine is, how it works, and how it can help control your symptoms and slow down your disease.
MS is a chronic autoimmune disease, in which your own immune system attacks the protective layer around your nerves by mistake. It does this using two different types of white blood cell, B cells and T cells.1
MS can cause many different symptoms, such as fatigue, difficulty walking, muscle spasms and vision problems.2
Ocrevus is a medicine for adults who have either primary progressive MS (PPMS), like you, or relapsing remitting MS (RRMS).3
Ocrevus is classified as a highly effective disease modifying treatment (HE DMT). In primary progressive MS, research studies show that Ocrevus treatment significantly slows down the progression of your disease when compared to placebo.4 For example, it delays the deterioration of walking speed, which can help you keep walking.5
Patients on Ocrevus also show fewer signs of the disease being active, such as brain lesions.3
The active ingredient in Ocrevus is ‘ocrelizumab’, a type of protein called a ‘monoclonal antibody’. Antibodies work by attaching themselves to specific targets in your body.6
Ocrevus targets and removes specific B cells – a type of white blood cell that forms part of the immune system and plays a role in MS.6
Removing these cells reduces inflammation and attacks on the myelin sheath (the protective membrane around your nerves that keeps brain signals moving through the body). This can help to control the frequency and severity of symptoms and delay the worsening (progression) of your disease.3
This animation shows how Ocrevus works in your body.
Adrian
who has relapsing remitting MS (RRMS), on Ocrevus IV infusion
Emma
Who has relapsing remitting MS, on Ocrevus subcutaneous injection
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. Please report suspected side effects to the MHRA through the Yellow Card scheme, via the Yellow card website www.mhra.gov.uk/yellowcard, or the free Yellow Card app available in the Apple App Store or Google Play Store. You should also report side effects to Roche Products Ltd. by emailing the Roche Drug Safety Centre at welwyn.uk_dsc@roche.com or calling +44 (0) 1707 367554. By reporting side effects you can help provide more information on the safety of this medicine.
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